Table 5

Cytokine production by splenocytea cultures from immunized BALB/c mice
Group Cytokine production (pg/mL)b
IFN-γ IL-4 IL-10
PBS 47.59 ± 4.63 37.26 ± 2.84 44.34 ± 2.77
PBudCE4.1 48.35 ± 1.86 33.70 ± 3.29 38.70 ± 2.70
pTgCPB 674.93 ± 83.36* 32.58 ± 3.72 34.60 ± 1.92
pTgCPL 585.14 ± 112.03* 32.34 ± 3.87 35.47 ± 1.94
pTgCPB/TgCPL 1182.23 ± 94.28*# 36.11 ± 3.51 34.57 ± 2.14

IFN, interferon; IL, interleukin, PBS, phosphate-buffered saline.

a Splenocytes were obtained from 3 mice per group and were collected at week 4 after the final immunization.

b Values for IFN-γ at 96 h. Values for IL-10 at 72 h. Values for IL-4 at 24 h.

*Compared with the PBS-adjuvant or pBudCE4.1 controls (P < 0.05); # compared with pTgCPB or pTgCPB (P < 0.05).

Zhao et al.

Zhao et al. BMC Infectious Diseases 2013 13:207   doi:10.1186/1471-2334-13-207

Open Data