Table 2 |
||||
Model parameter values and distributions | ||||
Infection parameters | Distributions | |||
Gonorrhoea | Reference | Chlamydia | Reference | |
Probability of infection being symptomatic | ||||
Male | β (0.9, 0.05) | [12-15] | β (0.30, 0.15) | [12,13] |
Female | β (0.4, 0.15) | [12-15] | β (0.15, 0.08) | [12,13] |
Duration of latent period (days) | U (3, 5) | [13,16-18] | U (12, 28) | [13,17,19] |
Duration of asymptomatic infection in the absence of treatment (days) | Γ (105, 35) | [12,13,20] | Γ (220, 188) | [12,19,21-24]* |
Duration of symptomatic infection in the absence of treatment (days) | Γ (105, 35) | [12,13,20] | Γ (112, 35) | [12,25] |
Duration of immunity following recovery (days) | Γ (7, 3.5) | - | Γ (45, 15) | - |
Transmission probability per sex act | ||||
Male to Female | β (0.2, 0.05) | [12,21,26,27] | β (0.16, 0.10) | [12,19,28,29] |
Female to Male | β (0.4, 0.10) | [12,21,26,30,31] | β (0.12, 0.06) | [12,19,28,29] |
Entries with no references are assumptions. U (l, u) denotes a uniform distribution with lower limit of l and upper limit of u; β (m, σ) denotes a beta distribution with mean of m and standard derivation of σ; Γ (m, σ) denotes a gamma distribution with mean of m and standard derivation of σ. Entries marked with ‘*’ indicate that the parameter has been adjusted in the model calibration process in order to generate realistic prevalences for gonorrhoea and chlamydia.
Hui et al.
Hui et al. BMC Infectious Diseases 2013 13:188 doi:10.1186/1471-2334-13-188