Table 1

Demographic and clinical characteristics of patients with bacteremic hospital-acquired pneumonia caused by Acinetobacter baumanniia
Demographic or characteristic Non-ventilator-associated (n = 48) Ventilator-associated (n = 96) p Value
n (% or IQRa)
Age in year 74 (54.8-81.8) 74 (59.0-80.0) 0.944
Gender, male 40 (83.3) 73 (76.0) 0.43
Acquired in ICU 12 (25.0) 84 (87.5)b <0.001
ICU admission after pneumonia 19 (39.6)c 86 (89.6) <0.001
Days of hospitalization prior to bacteremia 14.5 (3.2-3.6) 22.5 (12.0-40.8) 0.021
Comorbidity
  Charlson comorbidity score 3 (2.0-5.0) 3 (2.0-5.0) 0.861
  Hypertension 22 (45.8) 47 (49.0) 0.86
  Coronary artery disease 14 (29.2) 15 (15.6) 0.091
  Congestive heart failure 6 (12.5) 19 (19.8) 0.392
  Cerebral vascular disease 7 (14.6) 27 (28.1) 0.111
  COPD 12 (25.0) 27 (28.1) 0.842
  Non-COPD chronic lung disease 5 (10.4) 15 (15.6) 0.551
  Alcohol 3 (6.3) 13 (13.5) 0.302
  Liver cirrhosis 4 (8.3) 5 (5.2) 0.481
  Chronic kidney disease 15 (31.3) 32 (33.3) 0.95
  Type 2 diabetes 10 (20.8) 35 (36.5) 0.086
  Collagen vascular disease 4 (8.3) 7 (7.3) 1
  Usage of immunosuppressants 18 (37.5) 32 (33.3) 0.757
  Usage of corticosteroids 7(14.6) 23 (24.0) 0.276
  Neutropenia 4 (8.3) 7 (7.3) 1
  Malignancy 22 (45.8) 28 (29.2) 0.073
   Hematologic malignancy 7 (14.6) 6 (6.3) 0.125
   Solid malignancy 17 (35.4) 23 (24.0) 0.211
  Previous shock 8 (16.7) 27 (28.1) 0.192
  Recent surgery 8 (16.7) 34 (35.4) 0.032
  Trauma 0 (0) 4 (4.2) 0.301
Proceduresd
  Abdominal drain 1 (2.1) 5 (5.2) 0.658
  Arterial line 5 (10.4) 36 (37.5) 0.001
  Central venous catheter 22 (45.8) 71 (74.0) 0.002
  Pulmonary artery catheter 6 (12.5) 20 (20.8) 0.319
  Foley catheter 28 (58.3) 78 (81.3) 0.006
  Hemodialysis 4 (8.3) 10 (10.4) 0.774
  Nasogastric tube 35 (72.9) 93 (96.9) <0.001
  Thoracic drain 0 (0) 7 (7.3) 0.095
  Total parental nutrition 1 (2.1) 8 (8.3) 0.273
  Tracheostomy 7 (14.6) 16 (16.7) 0.936
Shockd 29 (60.4) 58 (60.4) 1
APACHE II scored 24 (17.3-31.8) 27 (21.3-34.8) 0.015
Radiological features
  Bilateral radiologic involvement 27 (56.3) 81 (84.4) 0.001
  Pleural effusion 20 (41.7) 32 (33.3) 0.425
Appropriate antimicrobial therapy 20 (41.7) 28 (29.2) 0.189
Combination antimicrobial therapy 4 (8.3) 7 (7.3) 1
Outcome
  14-day mortality 21 (43.8) 30 (31.3) 0.196

aData are median value (interquartile range) for continuous variables and number of cases (%) for categorical variables. IQR = interquartile range; ICU = intensive care unit; COPD = chronic obstructive pulmonary disease; APACHE = Acute Physiologic and Chronic Health Evaluation.

bOther patients were cared in a respiratory care center, respiratory ward, or common ward.

cTwelve acquired pneumonia in an ICU and 7 outside an ICU, all of them received mechanical ventilation after pneumonia.

dAt the time the blood culture was obtained.

Yang et al.

Yang et al. BMC Infectious Diseases 2013 13:142   doi:10.1186/1471-2334-13-142

Open Data