Table 2

Summary of the number and rates of children with candidias per 1,000 children with hospital admission/year (bold font) and specific candidiasis diagnoses per 1,000 children with hospital admission/year (non-bold font) in HIV-infected children and HIV-uninfected children in Spain from 1997 to 2008
HIV-uninfected children HIV-infected children
Description ICD-9 codex No. Rate (95% CI) No. Rate (95% CI)
All candidiasis 112.XX 26 5.0 (3.1; 6.9) 141 107.0 (90.1; 125.7) (*)
Non-invasive Candida mycosis (Non-ICM) 16 3.1 (1.6; 4.6) 120 91.8 (75.4; 108.3) (*, †)
   Candidiasis of mouth 112.0 13 2.5 (1.1; 3.8) 104 79.6 (64.6; 94.7) (*)
   Candidiasis of vulva and vagina 112.1 0 - 2 1.5 (0; 3.6)
   Candidiasis of other urogenital sites 112.2 0 - 4 3.1 (0.1; 6.1)
   Candidiasis of skin and nails 112.3 3 0.6 (0; 1.2) 5 3.8 (0.5; 7.2) (*)
   Candidal otitis external 112.82 0 - 1 0.7 (0; 2.3)
   Candidal esophagitis 112.84 0 - 12 9.2 (4.0; 14.4)
Invasive Candida mycosis (ICM) 10 1.9 (0.7, 3.1) 21 16.1 (9.2; 23.0) (*)
   Disseminated candidiasis 112.5 1 0.2 (0; 0.6) 3 2.3 (0; 4.9) (*)
   Candidal enteritis 112.85 0 - 5 3.8 (0.5; 7.2)
   Other candidiasis of other specified sites 112.89 6 1.1 (0.2; 2.1) 7 5.3 (1.4; 9.3) (*)
   Candidiasis of unspecified site 112.9 1 0.2 (0; 0. 6) 4 3.1 (0.1; 6.1) (*)
   Neonatal candida infection 771.7 2 0.4 (0; 0.9) 2 1.5 (0; 3.6)

Abbreviations: ICM, invasive candidiasis mycosis; HIV, Human immunodeficiency virus; ICD-9, data are coded according to the International Classification of Diseases (9th revision, Clinical Modification [ICD-9-MC]); Rate, events per 1,000 children with hospital admission/year; 95% CI, 95% of confidence interval.

(†): Significant differences between groups of study within a candidiasis diagnosis category (p < 0.001).

(*): Significant differences between Non-ICM and ICM categories within a study group (p < 0.001).

Álvaro-Meca et al.

Álvaro-Meca et al. BMC Infectious Diseases 2013 13:115   doi:10.1186/1471-2334-13-115

Open Data