Table 2

Voriconazole dosing characteristics, drug level monitoring, and duration of therapy
Voriconazole therapy Median value[(IQR]
Voriconazole serial drug levels (mg/L)
Initial drug level (n = 108) 2.35 [0.7, 3.8]
Second drug level (n = 51) 2.00 [0.5, 3.5]
Third drug level (n = 26) 1.35 [0.6, 7.7]
Voriconazole loading dose (mg/dose; n = 59) 400 [350, 480]
Voriconazole maintenance dose (mg/dose; n = 107) 260 [200,300]
Patient weight (kg; n = 107) 71.3 [60.5, 85.8]
Duration of voriconazole therapy in days (n = 85) 35 [13, 92]
Days between initiation of voriconazole to first drug level (n = 100) 11 [3,164]
Hours between last dose and trough drug level (n = 64) 11.3 [8.9-12.0]

Chu et al.

Chu et al. BMC Infectious Diseases 2013 13:105   doi:10.1186/1471-2334-13-105

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