Table 1

Demographic characteristics, univariable analysis between patients with ICU fungal HAIs and patients without ICU HAIs
Variables No HAI Fungal HAI p value
n = 1674(%) n = 186(%)
Age, years mean ± SD, 67.5 ± 18.0 71.6 ± 16.0 0.001
APACHE II score, mean ± SD 22.5 ± 7.6 24.7 ± 7.0 <0.001
ICU stay before infection, mean ± SD 6.9 ± 5.7 9.8 ± 7.1 <0.001
Length of ICU stay, mean ± SD 6.9 ± 5.7 20.9 ± 14.7 <0.001
Total parenteral nutrition use before infection, days, mean ± SD 6.9 ± 6.7 19.2 ± 1.7 <0.001
Total parenteral nutrition use (yes) 44(2.6) 36(19.4) <0.001
Gender (male) 1192(71.2) 131(70.4) 0.865
Service (surgical) 643(38.4) 105(56.5) <0.001
Main diagnosis(yes)
 Neoplasms 356(21.3) 40(21.5) 0.939
 Digestive system 334(20.0) 54(29.0) 0.003
 Respiratory system 272(16.2) 21(11.3) 0.078
 Genitourinary system 174(10.4) 14(7.5) 0.218
 Sepsis 51(3.0) 13(69.9) 0.005
7days before fungal infection with antibiotic therapy 1042(62.2) 141(75.8) <0.001
Mortality in ICU 305 (18.2) 56 (30.1) <0.001
Invasive procedures (yes)
Central venous catheter 1550(92.6) 178(95.7) <0.001
Mechanical ventilator 1139(68.0) 148(79.6) 0.001
Urinary catheter 854(51.0) 123(66.1) <0.001
Wound drainage 1550(92.6) 178(95.7) <0.001
Hemodialysis 417(24.9) 65(34.9) 0.003

SD, Standard deviation; APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit; HAI, healthcare-associated infection.

Yang et al.

Yang et al. BMC Infectious Diseases 2013 13:10   doi:10.1186/1471-2334-13-10

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