Table 3 |
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|
Results of 2009 pandemic influenza A (H1N1) antibodies before and after the pandemic in 60 vaccinated and 90 unvaccinated health care workers at a children's hospital in Taiwan |
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|
All (N = 150) |
Vaccinated (N = 60) No. (%) |
Unvaccinated (N = 90) |
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|
|
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|
All No. (%) |
High-risk (N = 40)3 No. (%) |
Low-risk (N = 50)3 No. (%) |
P value1 |
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|
|
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|
Seroprotective |
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|
Baseline2 |
7 (4.7%) |
2 (3.3%) |
5 (5.6%) |
3 (7.5%) |
2 (4.0%) |
0.652 |
|
Second2 |
13 (8.7%) |
2 (3.3%) |
11 (12.2%) |
8 (20.0%) |
3 (6.0%) |
0.056 |
|
Third2 |
52 (35.4%) |
34 (56.7%) |
18 (20.0%) |
12 (30.0%) |
6(12.0%) |
0.061 |
|
Seroconversion |
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|
1st to 2nd sera |
6 (4.0%) |
0 (0.0%) |
6 (6.7%) |
5 (12.5%) |
1 (2.0%) |
0.085 |
|
2nd to 3 rd sera |
39 (26.5%) |
32 (53%) |
7 (7.8%) |
4 (10.0%) |
3 (6.0%) |
0.695 |
|
1st to 3 rd sera |
45 (30.6%) |
32 (53%) |
13 (14.4%) |
9 (22.5%) |
4 (8.0%) |
0.071 |
|
GMT (95% CI) |
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|
Base line |
11.0 (10.7-12.0%) |
11.0 (10.5-12.6) |
11.2 (10.4-12.1) |
12.1 (10.5-13.9) |
10.6 (9.7-11.5) |
0.049 |
|
Second |
12.4 (11.4-13.6%) |
11.4 (10.4-12.4) |
13.2 (11.5-15.1) |
16.0 (12.6-20.3) |
11.3 (9.9-12.9) |
0.013 |
|
Third |
19.2 (16.6-22.1%) |
31.4 (23.8-36.8) |
14.0 (12.0-16.3) |
18.3 (14.0-24.1) |
11.3 (9.8-13.1) |
0.003 |
|
|
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|
Abbreviations: GMT: geometric mean titer; CI: confidence interval. 1 Comparisons were made between high- and normal-risk groups, using Chi-square or Fisher exact tests. 2 See text and Figure 2 for definitions of baseline, second, and third samples. 3 See text for definitions of high- and low-risk. |
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|
Yen et al. BMC Infectious Diseases 2012 12:89 doi:10.1186/1471-2334-12-89 |
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