Table 2

Minor and major resistance-associated mutations to protease inhibitors (PIs), nucleoside reverse transcriptase inhibitors (NRTIs) and non-NRTIs of HIV-1 strains from untreated pregnant women in Gabon

Subtype

n/N

PIs

NRTIs

non-NRTIs


A

2/21

L10V

-

V106I, V179I

1/21

-

L210W*

E138A

2/21

-

-

V179I

16/21

-/ND

-/ND

-/ND

D

1/1

-

-

V179I

F

3/5

L10V

-

-

2/5

-

-

-

G

1/11

L10I

ND

ND

1/11

L10I, V11I

ND

ND

1/11

L10I, V11I, M46I*

ND

ND

1/11

-

V118I

-

1/11

-

-

A98S

2/11

-

-

V179E

4/11

-

-/ND

-/ND

H

2/2

-/ND

-

-

CRF02_AG

2/50

L10I

-

-

2/50

L10V

-

-

1/50

L10V, L33F

-

-

1/50

L10V, T74S

-

-

2/50

E35G

-

-

1/50

M46I*

-

V90I

1/50

-

T69S

-

2/50

-

-

V90I

1/50

-

-

V90I, V179I

1/50

-

-

K101Q

1/50

-

-

K103R

2/50

-

-

V179I

33/50

-

-/ND

-/ND

CRF06_cpx

2/2

-

-

-

CRF11_cpx

1/2

L10I

-

-

1/2

-

-

-

Und

3/13

L10I

-

-

1/13

L10I

-

V106I

2/13

L10V

-/ND

-/ND

1/13

L10V

-

V179I

1/13

L10I, A71T

-

V179I

1/13

-

A62V

-

1/13

-

V118I

-

3/13

-

-

-


n, number of HIV-1 strains with resistance-associated mutations to PIs, NRTIs and non-NRTIs; in boldface, major mutation; -, no mutation; ND, not done; *, major mutation according to the list of investigations on transmitted ARVs resistance-associated mutations in untreated individuals [16]

Caron et al. BMC Infectious Diseases 2012 12:64   doi:10.1186/1471-2334-12-64

Open Data