IgG lineblot [recomBlot, Mikrogen]; Serum 1:271 dilution; CSF sample, 1:10 dilution. Both samples with equal total IgG-concentrations (27 mg/l). Figure 1B IgM lineblot [recomBlot, Mikrogen]; Serum sample diluted 1:3800; CSF sample diluted 1:10. Both samples with equal total IgM-concentrations (0.392 mg/l). Results from CSF analysis were positive for borrelia specific intrathecal IgG antibody production. The intensity of the reactive IgG and IgM bands [Optical Density, OD] was significantly stronger in the CSF sample than in the serum and the specific antibody index [AI] was strongly positive with 20.6.
Borde et al. BMC Infectious Diseases 2012 12:344 doi:10.1186/1471-2334-12-344