|Overview of studies with data on anal HPV detection among men who have sex with men aged ≤ 25 years|
|Author, year||Study setting||Selection criteria||No. MSM||No. MSM <=25a||Sample collection method||HPV DNA testing method||HPV types tested|
|(i) Kiviat, 1993 ; (ii) Critchlow, 1998 ||(i) Homosexual men attending an STD clinic in Seattle (ii) Homosexual men attending a community-based clinic for HIV screening in Seattle||(i) Age 16–50; being homosexual or bisexual. (ii) Age ≥18; having sex with other men||854||58b||Clinician collected||PCR; primers MY09 and MY11||PCR: 6,11,16,18,31 33, 35,39 and 45|
|Moscicki, 2003 ||Adolescents in primary care centres in 13 US cities who were at high risk of HIV infection||Age 13–18; having high-risk behaviours and/or injecting drug use||83||25c||Clinician collected||PCR, primers MY09, MY11 and HMB01||16,18,31,33,39,42, 44,45,51,52, 56 and 58|
|Nyitray, 2011||MSM from the general population, universities, STD clinics and organized health care systems in Sao Paulo, Cuernavaca, Tampa.||Age 18–70; having no prior penile or anal cancer or genital warts and no current HIV/STD diagnosis||176||46||Clinician collected||PCR;the QIAamp Media MDx kit (Qiagen); primers PGMY09/11||6,11,16,18,26,31,33, 35,39,40,42,45, 51–56,58,59,61,62,64, 66–73,81-84, IS39 and CP6108|
|Gilbert, 2011 ||MSM recruited from bars, festivals, associations, community events, bathhouses, and businesses in Vancouver||Age ≥19; identifying as a man who has ever had sex with men||178||30||Self collected||PCR; PCR and Linear Array kit (Roche); primers PGMY.||36 types including 6,11,16,18|
|Goldstone, 2011||MSM in a randomized, placebo-controlled, double-blinded trial of HPV vaccination in 14 countries||Age 16–26; having ≤ 5 lifetime male and/or female sexual partners; having had penetrative intercourse, including oral sex||602||539||Clinician collected||PCR; QIAamp DNA kit (Qiagen); primers based on published L1, E6 and E7 sequences.||6,11,16,18, 31,33,35,39, 45,51,52, 56, 58 and 59|
a Number of HIV negative MSM ≤ 25 years old for whom data on anal HPV DNA was provided by the authors.
b Combined data from two separate studies (i and ii) provided by the author.
c 58 men who were HIV positive were excluded.
Zou et al.
Zou et al. BMC Infectious Diseases 2012 12:341 doi:10.1186/1471-2334-12-341