Table 6

Significant clinical variables in the bivariate analysis of patients with respect to mortality, [n (%)] except where indicated
Total patients (n = 245) Colonised (n = 106) Aspergillosis (n = 139)
Died (n = 76) Survived (n = 169) p Died (n = 13) Survived (n = 93) p Died (n = 63) Survived (n = 76) p
Days to isolation (X ± SD) 13.0 ± 14.2 9.2 ± 8.5 0.012 6.5 ± 8.5 7.7 ± 6.3 0.126 14.3 ± 14.8 10.8 ± 10.2 0.153
Smokers 17 (22.4) 21 (12.4) 0.047 2 (15.4) 12 (12.9) 0.805 15 (23.8) 9 (11.8) 0.063
COPD 49 (64.5) 124 (73.4) 0.158 8 (61.5) 65 (69.9) 0.549 41 (65.1) 59 (77.6) 0.101
Malignancies 21 (27.6) 17 (10.1) 0.001 4 (30.8) 6 (6.5) 0.015 17 (27.0) 11 (14.5) 0.089
Charlson (X ± SD) 3.20 ± 2.64 2.34 ± 1.85 0.012 4.1 ± 3.2 2.2 ± 1.7 0.019 3.0 ± 2.5 2.5 ± 2.0 0.376
McCabe (Non fatal) 33 (43.4) 114 (67.5) 0.001 2 (15.4) 63 (67.7) 0.001 31 (49.2) 51 (67.1) 0.032
APACHE II (X ± SD) 16.3 ± 7.7 11.7 ± 5.9 0.001 14.0 ± 7.9 11.3 ± 5.8 0.191 16.8 ± 7.6 12.3 ± 6.1 0.001
ICU admission 32 (42.1) 26 (15.4) 0.001 4 (30.8) 11 (11.8) 0.086 28 (44.4) 15 (19.7) 0.002
ICU stay (days; X ± SD) 6.9 ± 7.6 6.8 ± 7.6 0.937 1.9 ± 5.8 0.7 ± 2.5 0.167 2.9 ± 6.0 1.5 ± 4.9 0.017
Dyspnoea 59 (77.6) 114 (67.5) 0.106 6 (46.2) 60 (64.5) 0.201 53 (84.1) 54 (71.1) 0.068
Infiltrates (X-ray / CT) 59 (77.6) 90 (53.3) 0.001 7 (53.8) 42 (45.3) 0.570 52 (82.5) 48 (63.2) 0.011
Cavitations (X-ray / CT) 19 (25.0) 19 (11.2) 0.006 1 (7.7) 4 (4.3) 0.487 18 (28.6) 15 (19.7) 0.237
Worsening X-ray signs 40 (52.6) 18 (10.7) 0.001 4 (30.8) 3 (3.3) 0.002 36 (57.1) 15 (19.7) 0.001
Steroids prior to admission 43 (56.6) 58 (34.3) 0.001 4 (30.8) 25 (26.9) 0.748 39 (61.9) 33 (43.4) 0.030
Steroids during admission 68 (89.5) 117 (69.2) 0.001 11 (84.6) 63 (67.7) 0.336 57 (90.5) 54 (71.1) 0.004
Antifungal treatment 60 (78.9) 81 (47.9) 0.001 7 (53.8) 24 (25.8) 0.052 53 (84.1) 57 (75.0) 0.187

Barberan et al.

Barberan et al. BMC Infectious Diseases 2012 12:295   doi:10.1186/1471-2334-12-295

Open Data