Table 2

Summary of histopathological findings
Feature Patient 1 Patient 2 Patient 3 Patient 4 Patient 5
Hepatocytes
Swelling mild marked mild mild marked
Regeneration Present Present Present Present Present
Steatosis Patchy Diffuse Patchy Patchy Diffuse
Cholestasis Present Present Present Present Present
Inflammation
NGI Portal/parenchymal Portal/parenchymal Portal/parenchymal Absent Absent
NNGI Portal/parenchymal Portal/parenchymal Portal/parenchymal Absent Absent
Langhans GC NGI/NNGI NGI/NNGI NGI/NNGI Absent Absent
NPs NGI NGI & parenchyma NGI parenchyma *portal tracts & parenchyma
LCs Portal/parenchymal; T dominant (admixed CD4+/CD8+) Portal/parenchymal; T dominant (admixed CD4+/CD8+) Portal/parenchymal; T dominant (admixed CD4+/CD8+) nil Portal/parenchymal; T dominant (dominant CD8+)
PCs Portal Portal Portal & parenchymal nil Portal & parenchymal
EPs Portal/parenchymal Portal/parenchymal Portal/parenchymal nil *Portal/parenchymal
HCs Portal/parenchymal Portal/parenchymal Portal/parenchymal nil Portal/parenchymal
Other
Architecture Maintained Mixed cirrhosis Maintained Cannot comment Maintained
Fibrosis Portal Fibrous linkages Portal Cannot comment nil
I/hepatitis Absent Absent Absent Cannot comment Present
ZN Paucibacillary Negative Negative Not done- no tissue Negative
PCR Positive Positive Positive Not done – no tissue Negative
Haemosiderin Present Present Present Present Present

Key: EPs: presence and dominant location of eosinophils; HC: presence and dominant location of histiocytes; I/hepatitis: interface hepatitis; Langhans GC: presence and location of Langhans giant cells; LCs: presence, dominant location & subtype of lymphocytes; NNGI: presence and location of non-necrotising granulomatous inflammation; NGI: presence and location of necrotising granulomatous inflammation; NPs: presence and dominant location of neutrophils; PCs presence and dominant location of eosinophils; PCR polymerase chain reaction; ZN ZiehlNeelsen stain.

Barr and Ramdial

Barr and Ramdial BMC Infectious Diseases 2012 12:257   doi:10.1186/1471-2334-12-257

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