Table 2

Factors associated with mortality in patients with E. coli or Klebsiella spp. bacteremia
Death Survival p RR (95 % CI)
(n = 81) (n = 306)
Demographics
 Men 57 (70.4) 207 (61.8) 0.1 1.36 (0.89-2.09)
 Age > 65 y 61 (75.3) 219 (71.6) 0.3 1.17 (0.74-1.83)
Place of acquisition
 Community acquired 13 (16) 97 (31.7) 0.003 0.41 (0.22-0.78)
 Health care associated 25 (30.9) 112 (36.6) 0.2 0.82 (0.53-1.24)
 Nosocomial 43 (53.1) 97 (31.7) <0.001 2 (1.36-2.93)
Origin of infection
 Urinary 38 (46.9) 177 (57.8) 0.05 0.71 (0.48-1.04)
 Biliary 8 (9.9) 41 (13.4) 0.26 0.76 (0.39-1.47)
 Unknown 9 (11.1) 28 (9.2) 0.36 1.18 (0.64-2.16)
 Intra-abdominal 11 (13.6) 23 (7.5) 0.07 1.63 (0.96-2.77)
 Pneumonia 8 (9.9) 20 (6.5) 0.21 1.41 (0.75-2.61)
 Catheter 3 (3.7) 13 (4.2) 0.56 0.89 (0.32-2.52)
Comorbidity
 Diabetes 21 (25.9) 91 (29.7) 0.3 0.86 (0.55-1.34)
 Ictus 15 (18.5) 55 (18) 0.51 1.03 (0.63-1.69)
 Dementia 16 (19.8) 50 (16.3) 0.28 1.2 (0.74-1.93)
 COPD 15 (18.5) 50 (16.3) 0.38 1.12 (0.69-1.84)
 Chronic renal failure 20 (24.7) 48 (15.7) 0.05 1.54 (1-2.37)
 Cardiac failure 15 (18.5) 41 (13.4) 0.16 1.34 (0.83-2.18)
 Liver cirrhosis 16 (19.8) 28 (9.2) 0.009 1.92 (1.23-3)
 Cancer 33 (40.7) 78 (25.5) 0.006 1.71 (1.17-2.51)
 Metastatic tumor 13 (16) 20 (6.5) 0.009 2.05 (1.28-3.3)
 Immunosuppression 16 (19.8) 49 (16) 0.25 1.22 (0.76-1.97)
 Charlson ≥3 60 (74.1) 149 (48.7) <0.001 2.43 (1.54-3.84)
Microbiology
E. coli 65 (80.2) 278 (90.8) 0.009 0.52 (0.33-0.82)
 Multidrug resistant 45 (55.6) 132 (43.1) 0.03 1.48 (1-2.19)
Presentation
 Sepsis severe or shock 57 (70.4) 68 (22.5) <0.001 4.9 (3.2-7.51)
 Adequate empirical therapy 34 (42) 164 (53.6) 0.04 0.69 (0.47-1.02)
 Adequate change for definitive therapy 29 (32.1) 109 (35.6) 0.33 0.88 (0.58-1.34)

Date are no. (%) of patients.

Peralta et al.

Peralta et al. BMC Infectious Diseases 2012 12:245   doi:10.1186/1471-2334-12-245

Open Data