Table 1

Baseline characteristics of 104 patients suffering from severe sepsis at day 1
All patients (n = 104) DAA + (n = 26) DAA − (n = 78) p value †
Age (years)* 64.0 ± 13.5 56.6 ± 15.0 66.5 ± 12.1 0.002
Gender (n)
Male 62 16 46 0.8
Female 42 10 32
Body mass index (BMI) * 26.4 ± 0.8 25.2 ± 2.5 26.6 ± 0.9 0.6
Heart rate (beats/min) * 84 ± 23.6 85 ± 20.8 84 ± 24.5 0.76
APACHE II score * 28.3 ± 5.4 28.6 ± 6.5 28.1 ± 5.0 0.9
Primary site of infection (n)
Lung 51 10 41
Urinary 6 2 4
Cerebral 5 2 3
Cardiac 12 4 8 0.3
Intra-abdominal 7 - 7
Skin 2 - 2
Unknown 21 8 13
CRP (mg/l)* 164 ± 126 206 ± 151 151 ± 115 0.2
Creatinine (mg/dl)* 2.6 ± 2.1 3.0 ± 2.3 2.5 ± 2.0 0.2
White blood cells (109/l)* 16.4 ± 8.0 16.0 ± 9.7 16.5 ± 7.5 0.4
Platelets (109/l)* 210 ± 117 202 ± 115 213 ± 118 0.5
aPTT (sec)* 40.7 ± 24.4 42.2 ± 25.5 40.2 ± 24.2 0.4
Antithrombin III (%)* 63.5 ± 19.5 61.4 ± 17.1 64.3 ± 20.6 0.8
D-dimer (μg/ml)* 5.0 ± 3.8 3.0 ± 2.0 5.5 ± 4.1 0.4
Bilirubin (mg/dl)* 1.7 ± 1.8 2.6 ± 2.3 1.4 ± 1.5 0.04
Death (n) 53 17 36 0.9

* Data are presented as mean ± standard deviation (SD).† p values are calculated for the comparison between DAA+ patients with DAA- patients.

Behnes et al.

Behnes et al. BMC Infectious Diseases 2012 12:217   doi:10.1186/1471-2334-12-217

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