Expression of CCR7 and CD62L in Flu-MP* peptide-specific CD8+T cells. (A) Phenotypic characterization by flow cytometry in one representative chagasic patient. (B) Significant differences were observed between central memory (double positive cells) T cells (TCM) and effector memory (double negative cells) T cells (TEM) (P < 0.008) from chagasic patients (white bars) or healthy donors (grey bars). No differences were found when the frequencies of TCM and TEM CD8+ T cells were compared between chagasic patients and healthy donors.
Lasso et al. BMC Infectious Diseases 2012 12:198 doi:10.1186/1471-2334-12-198