Table 2

Specific symptoms and responses to therapy of the 13 patients with probable late Lyme disease
Patient Exposure History Presenting Symptom/signs Duration Symptoms Treatment Outcome
1 Non-diagnostic skin lesion not treated. (See figure 2) Arthralgias, neck stiffness, fatigue; Olecranon bursitis 12 months Doxycycline 4 weeks All symptoms resolved. No Relapse
2 Unknown Arthralgias: hip; Headache 5 years Doxycycline 7 weeks 80% Improved. No relapse
3 Tick bite with cellulitis Rx with cephalexin Arthralgias: jaw, arm; Fatigue, memory problems 3 months Amoxicillin 4 weeks 95% improved. No relapse
4 Unknown Back pain 18 months Unknown Unknown
5 Spider bite, Rx with erythromycin Arthralgias, Poor memory; Night sweats 15 months Ceftriaxone 3 weeks; Amoxicillin 4 weeks Improved. Relapsed
6 Unknown Memory loss w/normal CSF dysthesias 6 months Doxycycline 12 weeks No improvement.
7 Viral symptoms with rash Rx with 5 day Zithromax Arthralgia; Fatigue 6 months Doxycycline 3 weeks 80% improved. Relapsed
8 Unknown Leg myalgia 12 months Doxycycline 12 weeks No clinically significant improvement
9 Unknown Arthralgias; Olecranon bursitis 12 months Doxycycline 6 weeks Marked improvement
10 Remote untreated EM 25 years prior Memory loss 12 months Doxycycline 4 weeks No improvement
11 Viral like illness Arthralgias; Olecranon bursitis, Edema 7 months Doxycycline 3 weeks Complete response. Relapsed
12 Round rash, no treatment Arthralgias 30 months Doxycycline 4 weeks Improvement. Relapsed
13 Unknown Fatigue, arthralgias, vertigo 18 months Doxycycline 8 weeks 50% improved. No relapse

Aucott et al.

Aucott et al. BMC Infectious Diseases 2012 12:173   doi:10.1186/1471-2334-12-173

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