Table 3

Residual risk of transmitting viral infection by transfusing seronegative units donated from 2000 to 2010
2000-2001 2002-2003 2004-2005 2006-2007 2008-2009 p-value of Poisson regression analysis
HIV
   No. of seroconvertors - - 17 10 16
   Incidence rate per 100,000 person-yr - - 1.99 1.31 1.83
   (95% CI)* (0~8.30) (0~6.51) (0~7.81)
   Residual risk (per 100,000 donations) - - 0.09 0.04 0.06 p = 0.745
   (95% CI) (0~1.43) (0~0.95) (0~1.14)
   RR (1 in) - - 1,080,244 2,534,406 1,813,998
HCV
   No. of seroconvertors 64 31 23 14 7
   Incidence rate per 100,000 person-yr 6.80 3.19 2.69 1.83 0.80
   (95% CI) (0~18.34) (0~11.00) (0~10.02) (0~7.97) (0~4.76)
   Residual risk (per 100,000 donations) 1.23 0.58 0.28 0.05 0.02 p = 0.001
   (95% CI) (0~6.14) (0~3.91) (0~2.65) (0~1.07) (0~0.65)
   RR (1 in) 81,431 173,611 357,197 1,991,405 4,560,879
HBV
   No. of seroconvertors 126 121 105 175 105
   Incidence rate per 100,000 person-yr 13.48 12.49 12.30 22.87 11.96
   (95% CI) (0~29.73) (0~27.95) (0~27.98) (1.16~44.58) (0~27.25)
   Residual risk (per 100,000 donations) 2.18 2.20 1.99 3.48 1.47 p = 0.885
   (95% CI) (0~8.72) 0~8.69) (0~8.30) (0~11.95) (0~6.83)
   RR (1 in) 45,891 49,515 50,218 28,754 67,826

*CI denotes confidence interval.

Kim et al.

Kim et al. BMC Infectious Diseases 2012 12:160   doi:10.1186/1471-2334-12-160

Open Data