Table 2

Sensitivity, Specificity, Positive and Negative predictive values of Total lymphocyte count cut-off for various CD4 groups
TLC cut-off (cells/mm3) Sensitivity (%) 95% CI Specificity (%) 95% CI PPV (%) NPV (%)
1000 72.22 46.52 to 90.31 94.44 72.71 to 99.86 100 91.7
CD4 count <200 1200 72.22 46.52 to 90.31 100 81.47 to 100.0 100 95.7
(cells/mm3) 1400 66.67 40.99 to 86.66 100 81.47 to 100.0 77.8 94.1
1600 55.56 30.76 to 78.47 100 81.47 to 100.0 65.6 91.7
1000 100 88.4 to 100 66.67 9.4 to 99.2 96.8 100
CD4 count 200–499 1200 100 88.4 to 101 67.67 9.4 to 99.3 96.7 66.7
(cells/mm3) 1500 96.67 82.8 to 99.9 100 29.2 to 100 100 75.0
1600 93.33 77.9 to 99.2 100 29.2 to 101 100 60.0
1700 95.45 77.2 to 99.9 63.64 30.8 to 89.1 84.0 87.5
CD4 count ≥500 1750 96.45 77.2 to 99.10 72.73 39.0 to 94.0 87.5 88.9
(cells/mm3) 1800 97.45 77.2 to 99.11 90.91 58.7 to 99.8 95.5 90.9
1900 98.45 77.2 to 99.12 100 71.5 to 100 100 91.7

TLC-Total lymphocyte count; PPV-Predictive positive value; NPV-Negative predictive value; 95% CI- 95% Confidence interval.

Obirikorang et al.

Obirikorang et al. BMC Infectious Diseases 2012 12:128   doi:10.1186/1471-2334-12-128

Open Data