Table 1

Baseline characteristics of the recruited children by IPD status
Characteristic IPD†
All recruited (n = 135) Non-confirmed (n = 118) Confirmed (n = 15) P-value§
Age (y) 0.787
 <2 58 (43.0) 50 (42.4) 7 (46.7)
 2-4 77 (57.0) 68 (57.6) 8 (53.3)
Sex (boy) 75 (55.6) 63 (53.4) 11 (73.3) 0.175
Race (White)§§ 116 (85.9) 101 (85.6) 13 (86.7) 1.000
Having been breastfed (yes) 103 (76.3) 92 (78.0) 10 (66.7) 0.340
Siblings (yes) 68 (50.4) 62 (52.5) 5 (33.3) 0.182
Having a parent smoking (yes) 31 (23.0) 29 (24.6) 2 (13.3) 0.519
Attending a community (yes) 54 (40.0) 45 (38.1) 8 (53.3) 0.276
Co-morbidity conditions§§§ (yes) 2 (1.5) --- 2 (13.3) 0.012*
Having received pneumococcal vaccine (yes) 47 (34.8) 41 (34.7) 4 (26.7) 0.773
Type (conjugate/polysaccharide) 41/6 36/5 3/1 0.448
Doses (n)§§§§ 0.551
 1 15 (31.9) 14 (34.1) 1 (25.0)
 2 18 (38.3) 17 (41.5) 1 (25.0)
 ≥3 14 (29.8) 10 (24.4) 2 (50.0)
Median (range) age at the first dose of vaccine (mo) §§§§ 6.5 (2–40) 6.0 (2–35) 9.5 (4–40) 0.250
Having received antibiotic therapy during the week before recruitment (yes) 40 (29.6) 38 (32.2) 1 (6.7) 0.067

Data are number (percentage within group) of children, except age at the first vaccination.

†In two cases the IPD status was not available.

§Significance of difference between confirmed and non-confirmed IPD groups (Fisher’s exact test or Mann Whitney U test). *: Statistically significant.

§§Other races included Afro/Afro-American (n = 13), Asian (n = 1) and mixed-races (n = 5).

§§§Sickle cell anaemia (n = 1) and cardiovascular disease. Both children did not receive pneumococcal vaccine.

§§§§ In children who received pneumococcal vaccine.

Riva et al.

Riva et al. BMC Infectious Diseases 2012 12:106   doi:10.1186/1471-2334-12-106

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