Table 2

Clinical features for JE and AES patients of suspected viral aetiology by outcome

Confirmed JE (n = 42)

AES suspected viral aetiology (n = 145)


Clinical Features at admission

Bad

Good

p-value

Bad

Good

p-value


No. patients

20

22

45

100

Age (years)

10 (1-14) [20]

4.5 (1-13) [22]

0.004

8 (1-14) [45]

6 (1-14) [97]

0.005

Number of males

5 (25) [20]

11 (50) [22]

0.121

13 (29) [45]

30 (31) [98]

1.000

Fever prior to admission (days)*

7 (3-13) [20]

5 (1-12) [22]

0.010

7 (1-14) [45]

5 (1-13) [100]

< 0.001

Altered sensorium

17 (85) [20]

13 (59) [22]

0.091

39 (89) [44]

55 (56) [98]

< 0.001

Duration of altered sensorium (days)

2 (1-5) [13]

2 (1-3) [10]

0.839

2 (1-7) [30]

1 (1-4) [43]

0.009

Modified Glasgow coma score*

11 (5-15) [20]

14 (7-15) [22]

0.001

11 (3-15) [44]

14 (4-15) [98]

< 0.001

Focal neurological deficit

9 (50) [18]

4 (18) [22]

0.046

17 (40) [43]

7 (7) [100]

< 0.001

Any seizure prior to admission

10 (77) [13]

15 (75) [20]

1.000

24 (77) [31]

67 (83) [81]

0.591

Episodes of seizure prior to admission

2 (1-12) [9]

2 (1-4) [14]

0.723

2 (1-12) [19]

2 (1-7) [48]

0.034

Neck stiffness

14 (82) [17]

9 (45) [20]

0.040

29 (71) [41]

49 (54) [91]

0.086

Vomiting

10 (71) [14]

13 (87) [15]

0.390

29 (81) [36]

47 (86) [55]

0.573

Days of vomiting prior to admission

3 (2-10) [8]

3 (1-7) [9]

0.400

3.5 (1-12) [26]

2 (1-8) [37]

0.019

Weight (kgs)

19.5 (9-30) [20]

13 (1-26) [22]

0.017

19 (4-35) [45]

15 (1-70) [90]

0.040

Axillary temperature (°C)

38.1 (36.7-40.0) [20]

37.8 (36.7-39.4) [20]

0.170

37.8 (36.1-40.0) [44]

37.8 (36.1-40.0) [86]

0.256

Pulse rate

(beats per min.)

101 (52-150) [20]

104 (76-130) [22]

0.905

106 (52-160) [44]

110 (64-170) [96]

0.972

Respiratory rate (breaths per min.)

28 (20-50) [20]

36 (20-80) [22]

0.064

28 (3-60) [45]

30 (16-90) [92]

0.158

Death prior to discharge

4 (20) [20]

0 (0) [22]

---

8 (18) [45]

0 (0) [100]

---

Neurological sequelae at discharge

16 (80) [20]

0 (0) [22]

37 (82) [45]

0 (0) [100]

Treatment

Phenytoin

6 (30) [20]

0 (0) [22]

0.007

18 (40) [45]

8 (8) [100]

< 0.001

Phenobarbitone

5 (25) [20]

3 (14) [22]

0.445

10 (22) [45]

10 (10) [100]

0.067

Dexamethasone

6 (30) [20]

4 (18) [22]

0.477

12 (27) [45]

22 (22) [100]

0.533

Mannitol

6 (30) [20]

2 (9) [22]

0.123

19 (42) [45]

15 (15) [100]

0.001


Median (range) or Number (%) [number of patients]. Significance of difference between groups by Fisher's Exact test or Mann-Whiney U test. : patients with one or more seizures before admission only : patients with vomiting prior to admission only * Parameters identified as independently associated with bad outcome in both AES groups.

Rayamajhi et al. BMC Infectious Diseases 2011 11:294   doi:10.1186/1471-2334-11-294

Open Data