Overwhelming postsplenectomy infection due to Mycoplasma pneumoniae in an asplenic cirrhotic patient: Case report
- Equal contributors
1 Department of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, 36, Sanhao Street, Shenyang, Liaoning, P.R.China
2 Department of intensive Care Unit, Shengjing Hospital, China Medical University, 36, Sanhao Street, Shenyang, Liaoning, P.R.China
BMC Infectious Diseases 2011, 11:162 doi:10.1186/1471-2334-11-162Published: 8 June 2011
Mycoplasma pneumoniae infection is usually self-limited, but some fulminant cases are fatal, even when occurring in previously healthy individuals. It can also be the cause of overwhelming postsplenectomy infection (OPSI).
We report a case of OPSI in a 41-year-old woman with hypersplenism associated with hepatitis B cirrhosis. We detected a significant Mycoplasma pneumoniae agglutination titer, but no evidence of infection with Chlamydia pneumoniae, Legionnella spp., or any other bacterial or fungal pathogens. She eventually died despite aggressive therapy.
M. pneumoniae could be an underestimated cause of OPSI, and should be suspected in fulminant infectious cases in asplenic patients.