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Open Access Case report

Overwhelming postsplenectomy infection due to Mycoplasma pneumoniae in an asplenic cirrhotic patient: Case report

Feng Xu1, Chao-Liu Dai1*, Xing-Mao Wu2 and Peng Chu1

Author Affiliations

1 Department of Hepatobiliary and Splenic Surgery, Shengjing Hospital, China Medical University, 36, Sanhao Street, Shenyang, Liaoning, P.R.China

2 Department of intensive Care Unit, Shengjing Hospital, China Medical University, 36, Sanhao Street, Shenyang, Liaoning, P.R.China

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BMC Infectious Diseases 2011, 11:162  doi:10.1186/1471-2334-11-162

Published: 8 June 2011

Abstract

Background

Mycoplasma pneumoniae infection is usually self-limited, but some fulminant cases are fatal, even when occurring in previously healthy individuals. It can also be the cause of overwhelming postsplenectomy infection (OPSI).

Case presentation

We report a case of OPSI in a 41-year-old woman with hypersplenism associated with hepatitis B cirrhosis. We detected a significant Mycoplasma pneumoniae agglutination titer, but no evidence of infection with Chlamydia pneumoniae, Legionnella spp., or any other bacterial or fungal pathogens. She eventually died despite aggressive therapy.

Conclusions

M. pneumoniae could be an underestimated cause of OPSI, and should be suspected in fulminant infectious cases in asplenic patients.

Keywords:
Overwhelming Postsplenectomy Infection; Mycoplasma Pneumoniae; DIC; ARDS