Table 4

Performance parameters of magnetic bead FM following blinded re-checking of discrepant results, compared with culture on MGIT 960 and Lowenstein-Jensen medium

Culture (MGIT + LJ)


Positive

Negative

Total


Magnetic bead FM (with blinded re-checking of discrepants)


Positive

76

12

88


Negative

31

163

194


Total

107

175

282


Sensitivity, %

(95% CI)

71.0%

(61.5 - 79.4)


Specificity, %

(95% CI)

93.1%

(88.3 - 96.4)


Overall accuracy, %

(95% CI)

84.8%

(80.0-88.7)


PPV, %

(95% CI)

86.4%

(77.4-92.8)


NPV, %

(95% CI)

84.0%

(80.0-88.7)


CI, confidence interval

PPV, positive predictive value

NPV, negative predictive value

ZN, Ziehl-Neelsen

FM, fluorescence microscopy

Albert et al. BMC Infectious Diseases 2011 11:125   doi:10.1186/1471-2334-11-125

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