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Kikuchi Fujimoto disease associated with cryptogenic organizing pneumonia: case report and literature review

Feng Hua12 and Lei Zhu1*

Author Affiliations

1 Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Feng Lin Road, Shanghai, 200032, PR China

2 Department of Pulmonary Medicine, Huzhou central Hospital, 198 Hongqi Road, Huzhou city, Zhejiang province, 313000, PR China

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BMC Infectious Diseases 2010, 10:64  doi:10.1186/1471-2334-10-64

Published: 11 March 2010



The association of Kikuchi Fujimoto disease (KFD) with cryptogenic organizing pneumonia (COP) is extremely rare. We report a case of simultaneous diagnosis of KFD and COP.

Case Presentation

A 33-year-old male presented with a 1-month cough illness and fever lasting for 5 days. The chest radiograph revealed double lower lobe infiltrate, which was unresponsive to antibiotics. A cervical lymph node was first found in the development of this disease. Bronchoscopy, bronchoalveolar lavage and lung biopsy established the diagnosis of COP, while a lymph node biopsy was consistent with KFD. The patient improved on steroids.


KFD and COP are possible part of a disease continuum, rather than separate entities.