Table 2

Comparison of characteristics of patients that are or are not part of a transmission cluster.

∈ cluster

∉ cluster

Multivariate Bin. Log. Regression

Count

Count

p-value

ODDS ratio

95% CI

p-value


# Patienten (n = 506)

169 (33.4%)

337 (66.6%)


Subtype B

143/169 (84.6%)

159/337 (47.2%)

< 0.001

-

Homosexual transmission

125/150 (83.3%)

117/258 (45.3%)

< 0.001

3.1

1.8 - 5.4

< 0.001

HBV+

56/167 (33.5%)

132/324 (40.7%)

0.12

-

HCV+

14/167 (8.4%)

20/325 (6.2%)

0.356

Syphilis+

68/169 (40.2%)

72/331 (21.8%)

< 0.001

-

Chlamydia+

61/151 (40.4%)

66/234 (28.2%)

0.013

-

Gender (male)

154/169 (91.1%)

219/337 (64.4%)

< 0.001

-

Caucasian origin

158/166 (95.2%)

195/335 (58.2%)

< 0.001

14.5

4.2 - 49.9

< 0.001

DRM

12/169 (7.1%)

21/337 (6.2%)

0,709

PHI

34/162 (21.0%)

38/302 (12.6%)

0.017

-


Median (IQR)

Median (IQR)

p-value


CD4+ T cells (cells/μl)

419.5 (311-580)

351 (192-550)

0.002

-

Age (years)

36 (31-42)

38 (32-45)

0.067

0.9

0.92 - 0.97

< 0.001


Values are given as counts per number of patients of which data was available. For the multivariate analysis, odds ratios are given with regard to being a member of a cluster (∈ cluster). The p-value for the Hosmer-Lemeshow test for the multivariate model is 0.876.

HBV, Hepatitis B Virus; HCV, Hepatitis C Virus; DRM, Drug Resistant Mutations; PHI, Primary HIV Infection; IQR, interquartile range; CI, confidence interval.

Chalmet et al. BMC Infectious Diseases 2010 10:262   doi:10.1186/1471-2334-10-262

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