Table 1

Number and cumulative frequencies of anti-TH and anti-TO levels overall and by blood culture isolates

Highest titer reached; Number (%)

All (n = 1,680)

Children with culture-confirmed typhoid fever (n = 16)

Children with non-Typhi serotypes of S. enterica (n = 49)

Children with other pathogenic bacteria (n = 113)

Children with no pathogenic bacteria isolated (n = 1,502)


Median age (Range)*

1.83

(14.81)

7.21

(11.96)

1.58

(6.73)

1.43

(11.83)

1.84

(14.81)


Anti-TH


≥1:640

15 (0.9)

3 (18.8)

5 (10.2)

0 (0)

7 (0.5)

1:320

24 (1.4)

6 (37.5)

6 (12.2)

0 (0)

12 (0.8)

1:160

36 (2.1)

11 (68.8)

7 (14.3)

0 (0)

18 (1.2)

1:80

46 (2.7)

12 (75.0)

7 (14.3)

1 (0.9)

26 (1.7)

1:40

85 (5.1)

12 (75.0)

9 (18.4)

3 (2.7)

61 (4.1)

No agglutination

1,595 (94.9)

4 (25.0)

40 (81.6)

110 (97.3)

1,441 (95.9)


Anti-TO


≥1:640

6 (0.4)

3 (18.8)

2 (4.1)

0 (0)

1 (0.1)

1:320

18 (1.1)

6 (37.5)

3 (6.1)

0 (0)

9 (0.6)

1:160

34 (2.0)

10 (62.5)

6 (12.2)

0 (0)

18 (1.2)

1:80

44 (2.6)

11 (68.8)

7 (14.3)

0 (0)

26 (1.7)

1:40

95 (5.7)

12 (75.0)

10 (20.4)

3 (2.7)

70 (4.7)

No agglutination

1,585 (94.3)

4 (25.0)

39 (79.6)

110 (97.3)

1,432 (95.3)


*P values: Group 1 vs 4 < 0.001; Group 2 vs 4 = 0.209; Group 3 vs 4 = 0.013

Ley et al. BMC Infectious Diseases 2010 10:180   doi:10.1186/1471-2334-10-180

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