Table 3

Univariate and multivariable linear regression analyses of association between clinical and demographic characteristics and total PEDsQL scores in thalassemia patients and parents
Characteristic Total PEDSQL score (patients) Total PEDSQL score (parents)
Univariateβ (95% CI) Multivariableβ (95% CI) Univariateβ (95% CI) Multivariableβ (95% CI)
Sex 1.49 (95% CI −9.09 to 12.07) p = 0.783 - 4.40 (95% CI −5.81 to 14.61) p = 0.401 -
Age at diagnosis 0.22 (95% CI −0.20 to 0.63) p = 0.311 - −0.01 (95% CI −0.42 to 0.39) p = 0.959 -
Age at first transfusion 0.15 (95% CI −0.22 to 0.53) p = 0.423 - −0.12 (95% CI −0.48 to 0.25) p = 0.528 -
Age at start of iron chelation −0.17 (95% CI −0.33 to 0) p = 0.046 −0.17 (95% CI −0.33 to 0) p = 0.046 −0.21(95% CI −0.36 to –0.06) p = 0.007 −0.21(95% CI −0.36 to –0.06) p = 0.007
Transfusion Frequency 7.04 (95% CI −5.56 to 19.65) p = 0.278 - 3.30 (95% CI −9.03 to 15.63) p = 0.602 -
Hepatomegaly 1.46 (95% CI −11.41 to 14.32) p = 0.278 - 5.11 (95% CI −7.29 to 17.51) p = 0.423 -
Hepatitis −2.91 (95% CI −13.88 to 8.06) p = 0.605 - −2.21 (95% CI 12.87 to 8.45) p = 0.686 -
Ferritin (>1300) 10.77 (95% CI −1.66 to 23.20) p = 0.095 - 3.05 (95% CI −9.28 to 15.38) p = 0.629
Iron Chelation 6.24 (95% CI −6.40 to 18.87) p = 0.337 - 10.95 (95% CI −1.08 to 22.98) p = 0.080 -

Caocci et al.

Caocci et al. BMC Blood Disorders 2012 12:6   doi:10.1186/1471-2326-12-6

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