Schematics of ZFN-cleavage sites within the hemoglobin, beta gene. This figure graphically illustrates the cleavage sites of the four ZFNs targeting sequences within the human-genomic context of the hemoglobin, beta gene. Hits (blue, green, and gold bars) represent targets along the gene (red bars). ZFN hits in the graphic are color-coded based on spacer size (5 bp = Blue; 6 bp = Green; 7 bp = Gold).
Wayengera BMC Blood Disorders 2012 12:5 doi:10.1186/1471-2326-12-5