Table 3

Comparative Analysis of Body Composition and Plasma Leptin levels among the Sickle Cell Anaemia Patients in the Steady and Unsteady States

^SCA Patients

Parameter

Steady

Males

Boys

Men

Total

Females

Girls

Women

Total

Unsteady

Males

Boys

Men

Total

Females

Girls

Women

Total

(n)

(6)

(10)

(16)

(9)

(6)

(15)

(7)

(2)

(9)

(10)

(5)

(15)

Age, yr

8.3 ± 1.4^b

25.7 ± 1.7^a

17.1 ± 1.6^a

8.7 ± 0.8

23.3 ± 2.2

14.5 ± 2.1

10 ± 1.2

17.5 ± 0.5

11.7 ± 1.5

10.9 ± 1.1

20.4 ± 2.2

15.1 ± 1.6

Weight, kg

17.8 ± 1.5^b

40.5 ± 1.0^a

31.9 ± 2.9^a,b

19.3 ± 2.8^a

43.3 ± 3.4^a

26.1 ± 3.8^a

18.8 ± 1.1

33.0 ± 0.2

22.0 ± 2.2

17.8 ± 1.4^c

35.8 ± 1.3

28.8 ± 2.5

BMI, kg/m²

18.4 ± 0.2^a

19.0 ± 0.3

18.7 ± 0.2

18.9 ± 0.5

19.6 ± 0.8^a

19.2 ± 0.5

19.7 ± 0.1^c

18.4 ± 0.4

19.4 ± 0.5

18.5 ± 0.5

17.9 ± 0.3

18.3 ± 0.4

FM, kg

3.6 ± 0.5^a,,b

8.2 ± 0.4

6.5 ± 0.5

4.6 ± 0.6

9.6 ± 0.9^a

6.0 ± 0.8

4.8 ± 0.5

8.9 ± 0.04

5.7 ± 0.7

4.4 ± 0.4

8.3 ± 0.9

5.7 ± 0.6

Leptin, ug/L

2.4 ± 0.03^a,b

2.1 ± 0.05

2.2 ± 0.04^a,b

4.2 ± 0.2^a

6.9 ± 0.2^a

5.3 ± 0.4^a

1.6 ± 0.08

1.8 ± 0.3

1.6 ± 0.09

2.9 ± 0.1

3.0 ± 0.1

3.0 ± 0.09

Leptin/FM

0.7 ± 0.08^b

0.27 ± 0.01^b

0.43 ± 0.06^b

1.04 ± 0.09^a

0.72 ± 0.06^a

0.98 ± 0.08^a

0.52 ± 0.05

0.2 ± 0.03

0.42 ± 0.05

0.7 ± 0.05^c

0.39 ± 0.06^c

0.6 ± 0.05^c

n = Number of cases, Data are mean ± SEM

^aP < 0.05 Significantly different in the same gender by age category (Stable vs. Unstable (Mann-Whitney U test)

^bP < 0.05 Significantly different in the between gender by age category in steady HbSS Patients (Mann-Whitney U test)

^cP < 0.05 Significantly different in the between gender by age category in unsteady HbSS Patients (Mann-Whitney U test)

^Age was set at ≤ 16 years for boys or girls and > 16 years for men or women

Iwalokun et al. BMC Blood Disorders 2011 11:2   doi:10.1186/1471-2326-11-2