Table 2

Validity of Mindstreams tests in discriminating participants with mild cognitive impairment (MCI; N = 30) from cognitively healthy elderly (N = 39).

Cognitive Domain

Mindstreams Test (outcome parameter)

AUC

SE

Asymptotic Significance

95% CI


MEMORY

Verbal Memory (accuracy, first repetition trial)

0.779

0.057

0.000

0.668–0.890

Verbal Memory (accuracy, second repetition trial)

0.838

0.05

0.000

0.741–0.936

Verbal Memory (accuracy, third repetition trial)

0.752

0.063

0.000

0.629–0.876

Verbal Memory Accuracy (accuracy, final repetition trial)

0.783

0.062

0.000

0.662–0.904

Verbal Memory (accuracy, all repetition trials)

0.859

0.048

0.000

0.765–0.953

Verbal Memory (accuracy, delayed recognition)

0.771

0.061

0.000

0.651–0.890

Non-Verbal Memory (accuracy, first repetition trial)

0.654

0.067

0.033

0.522–0.786

Non-Verbal Memory (accuracy, second repetition trial)

0.698

0.069

0.006

0.563–0.833

Non-Verbal Memory (accuracy, third repetition trial)

0.712

0.065

0.003

0.585–0.839

Non-Verbal Memory Accuracy (accuracy, final repetition trial)

0.773

0.061

0.000

0.654–0.892

Non-Verbal Memory (accuracy, all repetition trials)

0.756

0.063

0.000

0.633–0.879

Non-Verbal Memory (accuracy, delayed recognition)

0.728

0.065

0.002

0.601–0.854


EXECUTIVE FUNCTION

Go-NoGo (accuracy)

0.736

0.065

0.001

0.608–0.863

Go-NoGo (performance index)

0.810

0.056

0.000

0.701–0.920

Problem Solving (accuracy)

0.768

0.059

0.000

0.653–0.884

Stroop Interference (performance index)

0.703

0.077

0.023

0.551–0.854

Catch Game (accuracy)

0.696

0.075

0.016

0.548–0.843


VISUAL SPATIAL

Visual Spatial Imagery (accuracy)

0.765

0.060

0.000

0.648–0.881


VERBAL

Verbal Function (accuracy, naming)

0.716

0.067

0.005

0.584–0.848

Verbal Function (accuracy, rhyming)

0.824

0.051

0.000

0.724–0.923


ATTENTION

Go-NoGo (RT)

0.771

0.063

0.000

0.648–0.893

Go-NoGo (standard deviation of RT)

0.706

0.066

0.006

0.576–0.835

Choice Reaction Time (performance index)

0.490

0.084

0.894

0.326–0.653


INFORMATION PROCESSING

Staged Information Processing, Low Load (performance index)

0.579

0.083

0.345

0.416–0.743

Staged Information Processing, Medium Load (performance index)

0.783

0.070

0.001

0.646–0.920

Staged Information Processing, High Load (performance index)

0.688

0.088

0.037

0.515–0.860


MOTOR SKILLS

Finger Tapping (inter-tap interval)

0.595

0.076

0.215

0.446–0.744

Finger Tapping (standard deviation of inter-tap interval)

0.625

0.080

0.101

0.469–0.782

Catch Game (time to first move)

0.521

0.082

0.797

0.360–0.682


Mindstreams outcome parameters with insufficient data (<13 data points per group) due to failed practice sessions (see Methods) were excluded. AUC = area under the curve SE = standard error CI = confidence interval RT = reaction time

Dwolatzky et al. BMC Geriatrics 2003 3:4   doi:10.1186/1471-2318-3-4

Open Data