Table 5

Mean homocysteine, red cell folate and vitamin B12 concentration at baseline and follow up according to treatment group
Baseline: mean (standard deviation) Follow-up: mean (standard deviation) Difference (95% confidence interval) P-value (paired t-test)
Homocysteine (micromol/L)
Placebo (n = 463) 13.4 (5.0) 14.3 (5.7) 0.88 (0.40,1.36) <0.001
B-Vitamins (n = 462) 13.5 (6.3) 10.5 (4.2) −3.06 (−3.53,-2.59) <0.001
Red cell Folate (nmol/L)
Placebo (n = 173) 895.0 (466.6) 1135.2 (666.8) 244.8 (151.0,338.7) <0.001
B-Vitamins (n = 183) 959.2 (464.1) 2181.5 (752.3) 1220.0 (1117,1341) <0.001
B 12 (pmol/L)
Placebo (n = 190) 317.6 (140.8) 315.3 (188.9) −2.3 (−26.4,31.1) 0.87
B-Vitamins (n – 196) 322.1 (150.8) 594.7 (271.9) 272.6 (235.2,310.0) <0.001

Note: Only small subsets of patients had homocysteine, folate and vitamin B12 measured at both baseline and follow up.

Gommans et al.

Gommans et al. BMC Geriatrics 2013 13:88   doi:10.1186/1471-2318-13-88

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