Table 3

The participants’ diseases and comparisons between participants with and without B6 deficiency
Variable All participants n=61 Participants with p-PLP deficiency n=30 Participants with normal p-PLP n=31 p-value
Gastrointestinal pain/ discomfort1 0 (0–6) 0 (0–4) 0 (0–6) 0.288
Bowel function1 0 (0–3) 0 (0–2) 0 (0–3) 0.167
Constipation1 (n=59) 2 (0–5) 2 (0–4) 2 (0–5) 0.336
Diarrhoea1 0 (0–2) 0 (0–2) 0 (0–2) 1.000
Constipation 33 (54.1%) 17 (56.7%) 16 (51.6%) 0.689
Diarrhoea 6 (9.8%) 4 (13.3%) 2 (6.5%) 0.529
Other abdominal diseases2 15 (24.6%) 5 (16.7%) 10 (32.3%) 0.198
Cancer 8 (13.1%) 3 (10.0%) 5 (16.1%) 0.530
Cardiovascular diseases3 49 (80.3%) 25 (83.3%) 24 (77.4%) 0.607
Cerebrovascular disease 20 (32.8%) 11 (36.7%) 9 (29.0%) 0.565
Hypertension (needing treatment) 28 (45.9%) 18 (60.0%) 10 (32.3%) 0.040
Venous thromboembolism 4 (6.6%) 3 (10.0%) 1 (3.2%) 0.310
Haematological diseases4 4 (6.6%) 2 (6.7%) 2 (6.5%) 1.000
Dementia 48 (78.7%) 24 (80.0%) 24 (77.4%) 0.852
Parkinson’s disease 2 (3.3%) 0 (0.0%) 2 (6.5%) 0.206
Cognitively impaired5 59 (96.7%) 30 (100%) 29 (93.5%) 0.206
Psychiatric diseases6 31 (50.8%) 15 (50.0%) 16 (51.6%) 0.929
Musculoskeletal diseases7 23 (37.7%) 12 (40.0%) 11 (35.5%) 0.796
Pulmonary diseases8 12 (19.7%) 5 (16.7%) 7 (22.6%) 0.607
Diabetes 5 (8.2%) 2 (6.7%) 3 (9.7%) 0.762
Thyroid disease 7 (11.5%) 3 (10.0%) 4 (12.9%) 0.803
Allergy 4 (6.6%) 3 (10.0%) 1 (3.2%) 0.310

1 The variables for gastrointestinal pain/ discomfort, bowel function, constipation and diarrhoea were graded 0–12, 0–4, 0–9, and 0–5 respectively.

2 Biliary or hepatic disease, previous abdominal surgery, other abdominal disease.

3 Heart disease, peripheral circulatory dysfunction, hypertension, stroke.

4 Anaemia, leukaemia.

5 Unable to give informed consent, dementia, use of anti-dementia drugs.

6 Psychosis, schizophrenia, neurosis, depression, anxiety.

7 Osteoporosis, Bechterew’s disease, arthritis, osteoarthritis, fibromyalgia.

8 Recurrent pulmonary infections, asthma, chronic obstructive pulmonary disease.

The results are given as median (range) or number (percent). p-values indicate the difference between the groups with and without B6 deficiency. n=61 if not specified.

Kjeldby et al.

Kjeldby et al. BMC Geriatrics 2013 13:13   doi:10.1186/1471-2318-13-13

Open Data