Open Access Open Badges Research article

Exploration of the association between quality of life, assessed by the EQ-5D and ICECAP-O, and falls risk, cognitive function and daily function, in older adults with mobility impairments

Jennifer C Davis123*, Stirling Bryan13, Rob McLeod2, Jessica Rogers2, Karim Khan4 and Teresa Liu-Ambrose2

Author Affiliations

1 Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute, The University of British Columbia, Research Pavilion, 7th floor, 828 West 10th Avenue, V5Z 1M9, Vancouver, BC, Canada

2 Department of Physical Therapy, University of British Columbia, 212-2177 Wesbrook Mall, V6T 1Z3, Vancouver, BC, Canada

3 School of Population & Public Health, University of British Columbia, 2206 East Mall Vancouver, BC V6T 1Z3, Vancouver, BC, Canada

4 Centre for Hip Health and Mobility, Robert HN Ho Research Centre, 2635 Laurel Street, V5Z 1M9, Vancouver, BC, Canada

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BMC Geriatrics 2012, 12:65  doi:10.1186/1471-2318-12-65

Published: 24 October 2012



Our research sought to understand how falls risk, cognitive function, and daily function are associated with health related quality of life (using the EuroQol-5D) and quality of life (using the ICECAP-O) among older adults with mobility impairments.


The EQ-5D and ICECAP-O were administered at 12 months post first clinic attendance at the Vancouver Falls Prevention Clinic. We report descriptive statistics for all baseline characteristics collected at first clinic visit and primary outcomes of interest. Using multivariate stepwise linear regression, we assessed the construct validity of the EQ-5D and ICECAP-O using three dependent measures that are recognized indicators of “impaired mobility” – physiological falls risk, general balance and mobility, and cognitive status among older adults.


We report data on 215 seniors who attended the Vancouver Falls Prevention Clinic and received their first clinic assessment. Patients had a mean age of 79.3 (6.2) years. After accounting for known covariates (i.e., age and sex), the ICECAP-O domains explained a greater amount of variation in each of the three dependent measures compared with the EQ-5D domains.


Both the EQ-5D and ICECAP-O demonstrate associations with falls risk and general balance and mobility; however, only the ICECAP-O was associated with cognitive status among older adults with mobility impairments.

Trial registration Identifier: NCT01022866

ICECAP-O; EQ-5D; Construct validity; Older adults; Falls