Table 3

The expression of GATA-4 and GATA-6 in different cell types of the gastrointestinal mucosa on the basis of conventional and double immunohistochemistry

Tissue

Cell type

GATA-4

GATA-6


Stomach

Corpus

Surface epithelial cells

++

++

Neck cells

+++

++

Parietal cells

+++

++

Neuroendocrine cells

-

-

Antrum

Surface epithelial cells

++

+

Neck cells

+++

++

Glandular cells

++

+++

Neuroendocrine cells

-

-

Duodenum

Villus enterocytes

+++

++

Crypt enterocytes

++

+++

Neuroendocrine cells

-

-

Goblet cells

-

+

Paneth cells

-

++

Colon

Surface colonocytes

-

+

Crypt cells

-

+++

Goblet cells

-

++

Neuroendocrine cells

-

-


The expression patterns based on the number of positive cells detected:

- no expression,

+ low expression; <20% of the cells positive

++ moderate expression; 20–60% of the cells positive

+++ abundant expression; >60% of the cells positive

Haveri et al. BMC Gastroenterology 2008 8:9   doi:10.1186/1471-230X-8-9

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