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Bayesian Posterior Probabilities that the Prevalence of Pathologic Esophageal Reflux During PPI Treatment is Greater than the Prevalence of False-Positive Values for Pathologic Integrated Esophageal Acidity and Time Esophageal pH < 4. |
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| Probability that Observed Prevalence of Pathologic Esophageal Reflux is Greater than Prevalence of False-Positive Values |
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| Period |
Integrated Esophageal Acidity |
Time Esophageal pH < 4 |
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| 24-hour |
0.139 |
0.985 |
| Nocturnal |
0.066 |
0.999 |
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Bayesian posterior probabilities were calculated using the values for the prevalence of false-positive values given in Table 1, the combined prevalence of pathologic esophageal reflux calculated from the index and 3rd studies, and a flat prior probability [8]. The calculations were for values of prevalence from 0 to 1.0 in steps of 0.05. The flat prior probability considered all prevalence values from 0 to 1.0 to be equally probable. | ||
Gerson et al. BMC Gastroenterology 2008 8:15 doi:10.1186/1471-230X-8-15 |
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