Table 5

Sensitivity, specificity and predictive values of NashTest for the diagnosis of NASH

NashTest diagnosis

Histological Diagnosis


Training Group n = 160

Validation Group n = 97

All patients n = 257


Se

Sp

PPV

NPV

Sensitivity

Specificity

PPV

NPV

Sensitivity

Specificity

PPV

NPV


NASH

11/28

39%

122/132

92%

11/21

52%

Prevalence = 0.18

122/139

88%

10/35

29%

61/62

98%

10/11

91%

Prevalence = 0.36

61/86

71%

21/63

33%

183/194

94%

21/32

66%

Prevalence = 0.25

183/225

81%

Borderline or NASH

96/103

93%

20/57

35%

96/133

72% Prevalence = 0.64

20/27

74%

44/56

79%

29/41

71%

44/56

79%

Prevalence = 0.58

29/41

71%

140/159

88%

49/58

50%

140/189

74%

Prevalence = 0.62

49/68

72%


Poynard et al. BMC Gastroenterology 2006 6:34   doi:10.1186/1471-230X-6-34

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