Table 1

Demographic and clinical parameters depending on Crohn's disease behaviour at diagnosis

Disease behaviour at diagnosis


Variable

B1 (N = 80)

B2 (N = 15)

B3 (N = 21)

Overall (N = 116)


Follow-up (yr)

10.8 ± 6.5

9.9 ± 4

10.4 ± 6.9

10.5 ± 6.4

Males

46 (57.5%)

12 (80%)

12 (57.1%)

70 (60.3%)

Months to diagnosis

44.6 ± 42.4

38.8 ± 45.9

26.2 ± 36.1

40.6 ± 42.1

A1

60 (75%)

9 (60%)

14 (66.6%)

83 (71.5%)

Positive family history

10 (12.5%)

2 (13.3%)

3 (14.2%)

17 (14.6%)

Location of disease

L1

12 (15%)

7 (46.6%)*

6 (28.5%)

25 (21.5%)

L2

25 (31.2%)

2 (13.3%)

3 (14.2%)

30 (25.8%)

L3

34 (42.5%)

5 (33.3%)

12 (57.1%)

51 (43.9%)

L4

9 (11.2%)

1 (6.6%)

0

10 (8.6%)

Current smoking

41 (51.2%)

6 (40%)

12 (57.1%)

59 (50.8%)

Continuous course

17 (21.2%)

3 (20%)

3 (14.2%)

23 (19.8%)

Extraintestinal disease

43 (53.7%)

6 (40%)

8 (38%)

57 (49.1%)

Immunosuppressives

38 (47.5%)

3 (20%)*

9 (42.8%)

50 (43.1%)

Major operations

14 (17.5%)

11 (73.3%)*

10 (47.6%)*

35 (30.1%)

At diagnosis

2 (2.5%)

9 (60%)*

7 (33.3%)*

18 (15.5%)

After diagnosis

12 (15%)

2 (13.3%)

3 (14.2%)

17 (14.6%)


Values are given as mean ± SD or number of patients; Values in parentheses are percentages; N, number; A1, age at diagnosis ≤ 40 years; B1, non-stricturing non-penetrating disease; B2, stricturing disease; B3, penetrating disease; L1, ileal location; L2, colonic location; L3, ileo-colonic location; L4, disease in the upper gastro-intestinal tract; Extraintestinal disease refers to manifestations recorded during the entire follow-up period; Major operations refer to bowel resections; *P < 0.05 vs B1;

Chatzicostas et al. BMC Gastroenterology 2006 6:21   doi:10.1186/1471-230X-6-21

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