High prevalence of Helicobacter pylori infection in Behcet’s disease
1 Health policy Research Center, Shiraz University of Medical Sciences, P.O. Box 71345–1414, Shiraz, Islamic Republic of Iran
2 Bushehr University of Medical Sciences, Bushehr, Islamic Republic of Iran
3 Rheumatology Research Center, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran
BMC Gastroenterology 2014, 14:58 doi:10.1186/1471-230X-14-58Published: 31 March 2014
Behcet’s disease (BD) is a multisystem disease of unknown etiology. There are several clues which may indicate an ethiopathogenesis role for Helicobacter pylori infection in this disease.
In a case control study in an out patient department, 48 patients with BD were compared to age, sex matched controls regarding presence of H. pylori infection by serology and urea breath test (UBT).
Ongoing H. pylori infection was more prevalent among patients with BD using result of UBT with odds ratio of 3.1 (95% CI: 1.34 – 7.26, PV < 0.001).
H. pylori infection may have a role in the pathogenesis of BD.