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Open Access Research article

Clinical impact of body mass index on bactibilia and bacteremia

Chang Seok Bang1, Jai Hoon Yoon1*, Youn Jeong Kim2, Jin Bong Kim1, Gwang Ho Baik1, Ki Tae Suk1, Yeon Soo Kim1 and Dong Joon Kim1

Author Affiliations

1 Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, South Korea

2 Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, South Korea

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BMC Gastroenterology 2014, 14:104  doi:10.1186/1471-230X-14-104

Published: 5 June 2014

Abstract

Background

The aim of this study was to evaluate the association between obesity and infected bile or bacteremia in patients with acute calculous cholecystitis.

Methods

Authors analyzed the medical records of 139 patients who had undergone cholecystectomy for the treatment of acute calculous cholecystitis from January 2007 to June 2013 in a single teaching hospital. Association of body mass index (BMI) with bactibilia and bacteremia was assessed using univariate and multivariate analysis. Clinical findings and biliary infection related data were recorded for the following variables: gender, age, alcohol and smoking history, the results of blood and bile cultures, cholesterolosis, diabetes, hypertension, and duration of the hospital stay.

Results

The microbial culture rate of bactibilia and bacteremia were 50.4% and 21.6%, respectively. In the univariate analysis, bacteremia was associated with bactibilia (OR: 4.33, p = 0.002). In the multivariate analysis for the risk factors of bactibilia, BMI and bacteremia were related with bactibilia (OR: 0.59, 95% CI: 0.42-0.84, p = 0.003) (OR: 3.32, 95% CI: 1.22-9, p = 0.02). In the multivariate analysis for the risk factors of bacteremia, BMI, bactibilia and age were related with bacteremia (OR: 0.76, 95% CI: 0.59-0.99, p = 0.04) (OR: 3.46, 95% CI: 1.27-9.45, p = 0.02) (OR: 1.05, 95% CI: 1.01-1.09, p = 0.02).

Conclusion

In this retrospective study, BMI was inversely correlated with bacteremia or bactibilia, which means obese or overweight patients are less likely to be associated with bacteremia or bactibilia in patients with acute calculous cholecystitis.

Keywords:
Bacteremia; Cholecystitis; Obesity