Additional file 1: Figure S1.

Effect of age of onset at diagnosis of CD and NOD2 variants on treatment. Th age of onset of CD in 202 patient with NOD2 variant (grey bars) or wild-type (white bars) alleles is compared regarding steroid-dependent or refractory course of disease (A), need for long-term immunosuppressive therapy with azathioprine (AZA) and methotrexate (MTX) (B) or anti-TNFɑ agents (C). Differences were compared using Kruskal-Wallis test. A p-value below ≤0.05 was considered to be significant and indicated with an asterix.

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Posovszky et al. BMC Gastroenterology 2013 13:77   doi:10.1186/1471-230X-13-77