|Effect of Gluten Contamination Elimination Diet on celiac serology, main clinical symptoms and histologic findings|
|Patient||Serology before1||Serology after1||Symptoms before||Symptoms after||Biopsy before||Biopsy after|
|2||High||Neg||Inadequate weight gain||None|
|3||High||Neg||Diarrhea, fatigue||None||Marsh 3a (RCD)||Refused|
|4||High||Neg||Constipation||None||Marsh 3 (RCD)|
|5||High||Weak Pos||None||None||Marsh 3a||Marsh 1|
|6||High||Weak Pos||Elevated transaminases||None||Marsh 2|
|7||High||Weak Pos||Constipation, fatigue||None||Marsh 1|
|8||High||Weak Pos||Diarrhea||None||Marsh 1|
|9||High||High||Diarrhea, abdominal pain, bloating||None||Marsh 3a (RCD)||Marsh 1|
|10||High||High||Fatigue, anxiety||Fatigue, anxiety||Marsh 3a (RCD1)|
|11||Weak Pos||Neg||Diarrhea, abdominal pain||None||Marsh 2||Marsh 0|
|12||Weak Pos||Neg||Diarrhea||None||Marsh 1|
|13||Weak Pos||Weak Pos||Inadequate weight gain||Inadequate weight gain|
|14||Neg||Neg||Diarrhea, bloating, fatigue||None||Marsh 0|
|15||Neg||Neg||Abdominal pain, fatigue||None||Marsh 3a (RCD), VCE: Atrophy||VCE : normal|
|16||Neg||Neg||Diarrhea, weight loss||None||Marsh 3b (RCD)||Lost to follow-up|
|17||Neg||Neg||Diarrhea, abdominal pain, bloating||Diarrhea, abdominal pain, bloating||Marsh 3a (RCD)||VCE : atrophy|
1 Celiac serology defined as negative, weak positive or high using the cut-offs provided by the ELISA kit manufacturer. Tissue transglutaminase (tTG) IgA was followed in 16/17 patients; anti-endomysial (EMA) IgA was followed in the remaining patient.
Pos, positive; RCD, refractory celiac disease; RCD1, refractory celiac disease type 1; VCE, video capsule endoscopy.
Hollon et al.
Hollon et al. BMC Gastroenterology 2013 13:40 doi:10.1186/1471-230X-13-40