Email updates

Keep up to date with the latest news and content from BMC Gastroenterology and BioMed Central.

Open Access Highly Accessed Research article

A nationwide population-based study of the inflammatory bowel diseases between 1998 and 2008 in Taiwan

Shu-Chen Wei1, Meng-Hung Lin2, Chien-Chih Tung13, Meng-Tzu Weng14, Jen-Shin Kuo15, Ming-Jium Shieh6, Cheng-Yi Wang1, Wen-Chao Ho2, Jau-Min Wong1* and Pau-Chung Chen789*

Author Affiliations

1 Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan

2 Department of Public Health, College of Public Health, China Medical University, Taichung, Taiwan

3 Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan

4 Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei, Taiwan

5 Department of Internal Medicine, Kang-Ning General Hospital, Taipei, Taiwan

6 Department of Oncology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan

7 Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, 17 XuZhou Road, Taipei, Taiwan

8 Department of Public Health, National Taiwan University College of Public Health, Taipei, Taiwan

9 Department of Environmental and Occupational Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan

For all author emails, please log on.

BMC Gastroenterology 2013, 13:166  doi:10.1186/1471-230X-13-166

Published: 6 December 2013

Abstract

Background

The incidence of the inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), has been increasing in Asia. We probed the nationwide registered database to assess the incidence, prevalence, gender distribution, age of diagnosis and the survival status of IBD patients in Taiwan.

Methods

A retrospective study was conducted to analyze the registered database compiled by the National Health Insurance provided by the Department of Health, Taiwan, from January 1998 through December 2008.

Results

A total of 1591 IBD patients were registered from 1998 to 2008 in Taiwan (CD: 385; UC: 1206). The incidence of CD increased from 0.19/100,000 in 1998 to 0.24/100,000 in 2008. The incidence of UC increased from 0.61/100,000 in 1998 to 0.94/100,000 in 2008. The prevalence of CD increased from 0.19/100,000 in 1998 to 1.78/100,000 in 2008. The prevalence of UC increased from 0.61/100,000 in 1998 to 7.62/100,000 in 2008. Male to female ratio for CD was 2.22 and 1.64 for UC. Age of registered for CD was predominantly between 20 to 39, and for UC between 30 to 49 years of age. The standardized mortality ratio (95% CI) was 4.97 (3.72–6.63) for CD and 1.78 (1.46–2.17) for UC, from 1998 to 2008 in Taiwan.

Conclusions

Using the Taiwan nationwide database for IBD, the incidence and prevalence of IBD in Taiwan significantly increased from 1998 to 2008. The mortality rate was higher for CD patients than UC patients, and both were higher than the general population.

Keywords:
Crohn’s disease; Ulcerative colitis; Incidence; Prevalence; Taiwan; Nationwide