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Open Access Open Badges Research article

Clinical utility and tolerability of JSPH-1 wireless esophageal pH monitoring system

Jun-Nan Li, Chun-Lun Liu* and Xiao-Hong Tao

Author Affiliations

Department of Gastroenterology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 404100, China

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BMC Gastroenterology 2013, 13:10  doi:10.1186/1471-230X-13-10

Published: 15 January 2013



Wireless esophageal pH monitoring system is an important approach for diagnosis of gastroesophageal reflux disease (GERD), the aim of this study is to test the tolerability and utility of the first wireless esophageal pH monitoring system made in China, and evaluate whether it is feasible for clinical application to diagnose GERD.


Thirty patients from Department of Gastroenterology of The First Affiliated Hospital of Chongqing Medical University who were suspected GERD underwent JSPH-1 pH capsule. The capsule was placed 5 cm proximal to the squamocolumnar junction (SCJ) by endoscopic determination, the data was recorded consecutively for 48 hours. Then all pH data was downloaded to a computer for analysis. The discomforts reported by patients were recorded.


30 patients were placed JSPH-1 pH capsule successfully and completed 24-hour data recording, 29 patients completed 48-hour data recording. One patient complained of chest pain and required endoscopic removal. No complications and interference of daily activities were reported during data monitoring or follow-up period. 48-hour pH monitoring detected 15 patients of abnormal acid exposure, on day1 detected 9 patients, the difference had statistical significance (P<0.01). Positive symptom index (SI) was identified in 3 patients with normal pH data in both 24-hours. In total, 48-hour monitoring increased diagnosis of GERD in 9 patients.


48-hour esophageal pH monitoring with JSPH-1 wireless pH monitoring system is safe, well tolerated and effective. It can be feasible for clinical application to diagnose GERD.

Esophagus; Abnormal acid exposure; Esophageal pH monitoring; Wireless pH monitoring system; Gastroesophageal reflux disease