Additional file 2.
Figure S2.Deletionk of Foxp3+Treg activates CD4+T cells to produce cytokines. (A) IFN-γ, IL-13, and IL-17A production after 10 days of Fox3+ Treg deletion. CD4+ cells were extracted from mesentric lymph nodes and stimulated for 48h. Cytokine concentrations were determined in culture supernatants by ELISA. Data shown are the tabular representation of the mean values ± SD of the concentration of the distinct secreted cytokines derived from five mice per group each analyzed in duplicate. (B) Comparison of the Foxp3-GFP-DTR mice treated with DTx versus the tow different control groups. Data shown are the corresponding p values analyzed by a two-tailed unpaired student’s t-test with a 95% confidence interval.
Format: TIFF Size: 3MB Download file
Boehm et al. BMC Gastroenterology 2012 12:97 doi:10.1186/1471-230X-12-97