Table 1

Comparison of baseline characteristics (a) between individuals with and without fatty liver at baseline and (b) between individuals with and without incident fatty liver at follow up
Baseline fatty liver status (a) Follow up fatty liver status (b)
Absent Present (a) Absent Present (b)
p value p value
n 2589 988 2159 430
Age (y) 46.27 ± 8.51 48.08 ± 8.69 <0.0001 46.06 ± 8.57 47.32 ± 8.11 0.005
% Men 1305(50.4%) 800(81.0%) <0.0001 999 (46.3%) 306 (71.2%) <0.0001
BMI (kg/m2) 22.94 ± 2.58 26.10 ± 2.42 <0.0001 22.66 ± 2.53 24.33 ± 2.32 <0.0001
Waist 77.00 ± 8.44 87.52 ± 6.68 <0.0001 75.93 ± 8.25 82.36 ± 7.22 <0.0001
Exercise
None 817(31.5%) 270(27.3%) .002 689 (31.9%) 128 (29.8%) 0.81
≤1time/week 359(13.9%) 183(18.5%) 297 (13.8%) 62 (14.4%)
>1time/week 1413(54.6%) 535(54.1%) 1173 (54.3%) 240 (55.8%)
% Smoker
Never 1821(70.3%) 490(49.6%) <0.0001 1581 (73.2%) 240 (55.8%) <0.0001
Past 293(11.3%) 238(24.1%) 215 (10.0%) 78 (18.1%)
Current 475(18.3%) 260(26.3%) 363 (16.8%) 112 (26.0%)
Alcohol (gm/day) 5.81 ± 7.07 7.68 ± 7.53 <0.0001 5.37 ± 6.82 8.01 ± 7.84 <0.0001
SBP (mmHg) 115.23 ± 13.82 112.39 ± 15.00 <0.0001 114.60 ± 13.49 118.36 ± 14.97 <0.0001
DBP (mmHg) 74.64 ± 9.89 80.08 ± 10.08 <0.0001 74.06 ± 9.71 77.53 ± 10.25 <0.0001

Triglyceride

(mmol/L)

Median

[IQR]

1.10

[0.80,1.51]

1.80

[1.33,2.44]

<0.0001

1.04

[0.77,1.41]

1.38

[1.04,1.91]

<0.0001
HDL-C (mmol/L) 1.54 ± 0.30 1.40 ± 0.23 <0.0001 1.56 ± 0.31 1.47 ± 0.27 <0.0001
HsCRP (mg/L) 0.82 ± 1.43 1.38 ± 1.75 <0.0001 0.77 ± 1.40 1.03 ± 1.58 <0.0001
Platelets (109/L) 246.14 ± 53.10 235.32 ± 50.57 <0.0001 244.73 ± 52.63 253.16 ± 54.90 0.003
Albumin (g/L) 45.6 ± 2.4 46.7 ± 2.5 <0.0001 45.4 ± 3.0 45.9 ± .2.3 <0.0001
ALT (U/L) 21.44 ± 15.19 38.39 ± 22.02 <0.0001 20.38 ± 11.67 26.69 ± 25.95 <0.0001
AST (U/L) 22.14 ± 7.11 27.99 ± 10.87 <0.0001 21.87 ± 6.93 23.46 ± 7.83 <0.0001
AST/ALT ratio 1.17 ± 0.36 0.82 ± 0.27 <0.0001 1.19 ± 0.36 1.03 ± 0.33 <0.0001
AST/platelet index 9.46 ± 3.97 11.62 ± 5.81 <0.0001 9.38 ± 3.74 9.86 ± 4.95 0.06

Fasting Glucose

(mmol/L)

5.10 ± 0.66 5.55 ± 1.13 <0.0001 5.06 ± 0.56 5.26 ± 1.01 <0.0001
Fasting Insulin (pmol/L) 59.48 ± 18.65 75.39 ± 27.89 <0.0001 58.91 ± 18.18 62.28 ± 20.64 0.002
HOMA-IR 1.95 ± 0.69 2.69 ± 1.16 <0.0001 1.92 ± 0.66 2.10 ± 0.81 <0.0001
MetS, n (%) 135 (5.2%) 293 (29.7%) <0.0001 92 (4.3%) 43 (10.0%) <0.0001

Data are presented as mean (SD), except where indicated.

Sung et al.

Sung et al. BMC Gastroenterology 2012 12:84   doi:10.1186/1471-230X-12-84

Open Data