Table 3

Multivariate analysis of factors related to severe thrombocytopenia

Multivariate Analysis


Factors

P value

Odds Ratio

95% Confidence Interval


BMI (< 24.5/≥ 24.5 Kg/m2)

0.280

ALB (≤ 4.1/> 4.1 g/dL)

0.412

ALK-p (≥ 97/< 97 U/L)

0.646

PLT (< 100,000/≥ 100,000/μL)

< 0.001

179.219

12.219-2628.602

HCV-RNA (log10, IU/mL) (≥ 5.95/< 5.95)

0.196

HCV genotype (1/2)

0.419

Ribavirin dose (≤ 24.58/> 24.58)

0.201

Rate of PLT decline at week 2 (early PLT decline, > 30%/≤ 30%)

0.003

45.742

3.524-593.689


Abbreviations: ALB: albumin; ALK-p: alkaline phosphatase; AST: aspartate aminotransferase; PLT: platelet; BMI: body mass index; C.I.: confidence interval; HCV: hepatitic C virus.

Lin et al. BMC Gastroenterology 2012 12:7   doi:10.1186/1471-230X-12-7

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