Table 1

Characteristics of 125 patients with chronic hepatitis C

Variables

Median (25th-75thpercentile values) or number (percentage)


Age (years)

57 (25-64)

Gender (male/female)

65/60 (52/48)

BMI (kg/m2)

24.8 (23.0-27.0)

Albumin (g/dL)

4.1 (3.9-4.4)

Total bilirubin (mg/dL)

0.7 (0.6-1.0)

AST (U/L)

107 (72-159)

ALT (U/L)

160 (109-259)

ALK-p (U/L)

96 (72-121)

PT INR

1.04 (1.01-1.08)

WBC (/mm3)

5,120 (4,403-6,083)

Hgb (g/dL)

14.4 (13.3-15.5)

Platelets (/μL)

125,000 (110,000-140,500)

Fibrosis (F1/2/3/4)

2/31/39/19 (1.6/24.8/31.2/15.2)#

Necroinflammatory activity (A0/1/2/3)

13/49/21/3 (10.4/38.2/16.8/2.4)#

Cirrhosis status (yes/no)

28/97 (22.4/77.6)

HCV-RNA (log10, IU/mL)

6.12 (5.39-6.66)

HCV genotype (1/2)

71/54 (56.8/43.2)

Splenomegaly (yes/no)

27/97 (21.6/77.6)§

Peg-IFN-α-2a/-α-2b

48/77 (38.4/61.6)

Dose of ribavirin (mg/day)

867 (800-1000)


Abbreivations: ALK-p: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BMI: body mass index; Hgb: hemoglobin; HCV: hepatitic C virus; PT INR: international normalized ratio of prothrombin time; WBC: white blood cells; Peg-IFN: pegylated-interferon.

#Only the patients undergoing liver biopsy were analyzed for fibrosis and necroinflammatory activity of liver tissue. F1-F4 represent fibrotic scores, and A0-A3 mean necroinflammatory scores, according to METAVIR scoring system [10].

§One patient had undergone splenectomy due to traumatic splenic rupture.

Lin et al. BMC Gastroenterology 2012 12:7   doi:10.1186/1471-230X-12-7

Open Data