Receiver Operating Characteristics Curve. To identify clinically significant findings in the gastrointestinal tract, fecal calprotectin had an area under the receiver operating characteristics (ROC) curve of 0.877 (95% CI 0.85-0.90) (Figure 2A). The AUC of fecal calprotectin to identify clinically significant findings was better in the lower intestinal tract (AUC 0.912, 95%CI 0.88-0.94) (Figure 2C) than in the upper intestinal tract (AUC 0.730, 95%CI 0.66-0-79, P < 0.001) (Figure 2B).
Manz et al. BMC Gastroenterology 2012 12:5 doi:10.1186/1471-230X-12-5