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Open Access Research article

Correlation between magnifying narrow band imaging and histopathology in gastric protruding/or polypoid lesions: a pilot feasibility trial

Takafumi Omori1, Yoshio Kamiya1, Tomomitsu Tahara1*, Tomoyuki Shibata1, Masakatsu Nakamura2, Joh Yonemura1, Masaaki Okubo1, Daisuke Yoshioka1, Takamitsu Ishizuka1, Naoko Maruyama1, Toshiaki Kamano1, Hiroshi Fujita1, Yoshihito Nakagawa1, Mitsuo Nagasaka1, Masami Iwata1, Tomiyasu Arisawa2 and Ichiro Hirata1

Author Affiliations

1 Department of Gastroenterology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan

2 Department of Gastroenterology, Kanazawa Medical University, 1-1 Daigaku, Uchinadamachi, Ishikawa 920-0293, Japan

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BMC Gastroenterology 2012, 12:17  doi:10.1186/1471-230X-12-17

Published: 22 February 2012

Abstract

Background

Several study showed usefulness of microscopic capillaries, seen by magnifying narrow band imaging (NBI) endoscopy for predicting histopathology among superficial depressed or flat elevated gastric neoplasia (GN). Here we assessed the diagnostic efficacy of magnifying NBI for predicting histopathology among gastric protruding/or polypoid lesions.

Methods

Using endoscopic pictures of magnifying NBI from 95 protruding/or polypoid lesions (19 fundic gland polyps: FGP, 47 hyperplastic polyps: HP, and 29 GN), fine mucosal patterns were classified into four categories: small round, prolonged, villous or ridge, and unclear patterns, and micro vascular patterns were classified into five categories: honey comb, dense vascular, fine net work, core vascular, and unclear patterns.

Results

Most suggestive micro vascular patterns for predicting FGP, and HP were honeycomb (sensitivity 94.7%, specificity 97.4%), and dense vascular patterns (sensitivity 93.6%, specificity 91.6%), respectively. Fine net work, core vascular, and unclear patterns presented higher specificity (97%, 100%, and 100%) for predicting GN, and diagnostic efficacy of combined of those patterns was favorable (sensitivity 86.2%, specificity 97.0%).

Conclusion

Micro vascular patterns by using magnifying NBI provides meaningful information for predicting the histopathology of gastric protruding/or polypoid lesions.

Keywords:
NBI; Stomach; Magnifying endoscopy; Polypoid lesions; Gastric cancer