Table 2

Four single nucleotide polymorphisms in the GNB1 gene in 265 HCV-1 and 195 HCV-2 infected patients receiving PEG-IFNα-RBV therapy with or without a RVR in a Chinese population in Taiwan
SNP Position inGNB1 Chromosome positiona Alleles HCV-1 HCV-2
HWE (Pvalue) MAF HWE (Pvalue) MAF
RVR (+) RVR (−) RVR (+) RVR (−)
rs10907185 (S1) Intron 7 1733219 A/G 0.2132 0.3009 0.2548 0.465 0.2785 0.2162
rs6603797 (S2) Intron 2 1765583 C/T 0.5854 0.1065 0.1401 0.4007 0.0981 0.0946
rs4648727 (S3) Intron 1 1776269 A/C 0.1309 0.3241 0.3429 0.8709 0.3513 0.2361
rs12126768 (S4) Intron 1 1778090 G/T 0.7439 0.2083 0.2756 1 0.2373 0.2162

Abbreviations: SNP, single nucleotide polymorphism; HWE, Hardy–Weinberg equilibrium; MAF, minor allele frequency.

a Chromosome positions refer to the sequence in the NCBI database (build 37.3).

Lim et al.

Lim et al. BMC Gastroenterology 2012 12:167   doi:10.1186/1471-230X-12-167

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