Table 1

Characteristics of HCV genotype 1 and 2 infected patients receiving PEG-IFNα-RBV therapy
HCV genotype 1 (HCV-1) HCV genotype 2 (HCV-2)
Total RVR (+) RVR (−) Pvalue Total RVR (+) RVR (−) Pvalue
Number of patients 265 108 157 - 195 158 37 -
Sex (males/females) 129/136 55/53 74/83 0.545 88/107 75/83 13/24 0.176
Age (mean ± SD) 52.17 ± 10.27 50.96 ± 10.97 52.99 ± 9.71 0.172a 51.62 ± 10.89 51.08 ± 10.92 53.89 ± 10.62 0.095a
BMI (mean ± SD) 24.6 ± 3.1 24.6 ± 3.0 24.6 ± 3.2 0.971a 24.5 ± 3.5 24.5 ± 3.7 24.5 ± 3.1 0.933a
Degree of inflammatory activity (A0/A1-3) 35/230 10/98 25/132 0.115b 22/173 19/139 3/34 0.498 b
Stage of fibrosis (F0/F1-4) 16/249 3/105 13/144 0.065 b 10/185 9/149 1/36 0.457 b
AST (U/L) (mean ± SD) 83.5 ± 57.1 80.7 ± 45.1 0.988 a 85.7 ± 65.5 75.2 ± 39.1 0.677 a
ALT (U/L) (mean ± SD) 132.2 ± 93.5 102.4 ± 57.6 0.018 a 122.9 ± 108 101.9 ± 60.7 0.329 a
PLT (×103/μl) (mean ± SD) 174.6 ± 62.3 163.7 ± 55.7 0.146 a 173.6 ± 53.5 155.5 ± 50.1 0.041 a
Viral load (× 106) 12.1 ± 16.4 7.0 ± 10.3 16.0 ± 18.8 <0.0001a 11.0 ± 19.0 10.0 ± 18.2 15.3 ± 21.8 0.217a

Abbreviations: RVR, rapid virological response; BMI, body mass index; AST, aspartate aminotransferase; ALT, alanine aminotransferase; PLT, platelet.

a Calculated by the Mann–Whitney U test.

b Calculated by the by χ2 test.

Lim et al.

Lim et al. BMC Gastroenterology 2012 12:167   doi:10.1186/1471-230X-12-167

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